5T89

Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6

Summary for 5T89

Entry DOI	10.2210/pdb5t89/pdb
Descriptor	Vascular endothelial growth factor A, Vascular endothelial growth factor receptor 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	receptor tyrosine kinase, growth factor, immunoglobulin domain, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	182190.52
Authors	Markovic-Mueller, S.,Stuttfeld, E.,Asthana, M.,Weinert, T.,Bliven, S.,Goldie, K.N.,Kisko, K.,Capitani, G.,Ballmer-Hofer, K. (deposition date: 2016-09-07, release date: 2017-02-01, Last modification date: 2020-07-29)
Primary citation	Markovic-Mueller, S.,Stuttfeld, E.,Asthana, M.,Weinert, T.,Bliven, S.,Goldie, K.N.,Kisko, K.,Capitani, G.,Ballmer-Hofer, K. Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A. Structure, 25:341-352, 2017 Cited by PubMed: 28111021 DOI: 10.1016/j.str.2016.12.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4 Å)

Structure validation