5T3M
Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7
Summary for 5T3M
Entry DOI | 10.2210/pdb5t3m/pdb |
NMR Information | BMRB: 30160 |
Descriptor | Mu-theraphotoxin-Hs2a (1 entity in total) |
Functional Keywords | toxin |
Biological source | Haplopelma schmidti (Chinese bird spider) |
Total number of polymer chains | 1 |
Total formula weight | 3999.78 |
Authors | Rahnama, S.,Sharma, G.,Mobli, M. (deposition date: 2016-08-25, release date: 2017-09-06, Last modification date: 2023-06-14) |
Primary citation | Rahnama, S.,Deuis, J.R.,Cardoso, F.C.,Ramanujam, V.,Lewis, R.J.,Rash, L.D.,King, G.F.,Vetter, I.,Mobli, M. The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant. PLoS ONE, 12:e0173551-e0173551, 2017 Cited by PubMed: 28301520DOI: 10.1371/journal.pone.0173551 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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