5OO3
Cdk2(F80C, C177A) with covalent ligand at F80C
Summary for 5OO3
Entry DOI | 10.2210/pdb5oo3/pdb |
Related | 5OO0 5OO1 |
Descriptor | Cyclin-dependent kinase 2, 1-(4-ethyl-2,3-dihydroquinoxalin-1-yl)propan-1-one (3 entities in total) |
Functional Keywords | covalent inhibitor, cysteine modification, kinase, allosteric inhibitor, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34530.14 |
Authors | Craven, G.,Morgan, R.M.L.,Mann, D.J. (deposition date: 2017-08-05, release date: 2018-08-29, Last modification date: 2024-01-17) |
Primary citation | Craven, G.,Affron, D.P.,Allen, C.E.,Greener, J.G.,Morgan, R.M.L.,Matthies, S.,Armstrong, A.,Mann, D.J. High-throughput kinetic analysis for target-directed covalent ligand discovery To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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