5OO1

Cdk2(F80C, C177A) covalent adduct with C37 at F80C

Summary for 5OO1

• Entry DOI: 10.2210/pdb5oo1/pdb
• Related: 5OO0
• Descriptor: Cyclin-dependent kinase 2, ~{N}-(4-pyrimidin-2-ylphenyl)propanamide (3 entities in total)
• Functional Keywords: covalent inhibitor, cysteine modification, kinase, allosteric inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 34539.11

Authors

Craven, G.,Morgan, R.M.L.,Mann, D.J. (deposition date: 2017-08-04, release date: 2018-08-29, Last modification date: 2024-01-17)

• Primary citation: Craven, G.,Affron, D.P.,Allen, C.E.,Greener, J.G.,Morgan, R.M.L.,Matthies, S.,Armstrong, A.,Mann, D.J.; High-throughput kinetic analysis for target-directed covalent ligand discovery; To be published,

Experimental method

X-RAY DIFFRACTION (2 Å)