5OML

Crystal structure of Trypanosoma Brucei PEX14 N-terminal domain in complex with small molecules to investigate the water envelope

Summary for 5OML

• Entry DOI: 10.2210/pdb5oml/pdb
• Descriptor: Peroxin 14, (3~{R})-3-[[1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-3-yl]carbonylamino]-3-phenyl-propanoic acid, SULFATE ION, ... (5 entities in total)
• Functional Keywords: peroxisomal translocation, ppi inhibition, protein-inhibitor complex, signaling protein
• Biological source: Trypanosoma brucei brucei
• Total number of polymer chains: 4
• Total formula weight: 33927.02

Authors

Ratkova, E.L.,Dawidowski, M.,Napolitano, V.,Dubin, G.,Fino, R.,Popowicz, G.,Sattler, M.,Tetko, I.V. (deposition date: 2017-08-01, release date: 2019-03-06, Last modification date: 2024-01-17)

• Primary citation: Ratkova, E.L.,Dawidowski, M.,Napolitano, V.,Dubin, G.,Fino, R.,Popowicz, G.,Sattler, M.,Tetko, I.V.; Crystal structure of Trypanosoma Brucei PEX14 N-terminal domain in complex with small molecules to investigate the water envelope; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)