5OML
Crystal structure of Trypanosoma Brucei PEX14 N-terminal domain in complex with small molecules to investigate the water envelope
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Peroxin 14 | polymer | 67 | 7754.9 | 4 | UniProt (Q8IEW2) Pfam (PF04695) | Trypanosoma brucei brucei | |
| 2 | E, I, L, P (A, B, C, D) | (3~{R})-3-[[1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-3-yl]carbonylamino]-3-phenyl-propanoic acid | non-polymer | 528.6 | 4 | Chemie (9YB) | |||
| 3 | F, G, J, M, N (A, B, C) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | H, K, O, Q (A, B, C, D) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 4 | Chemie (BME) | |||
| 5 | R, S, T, U (A, B, C, D) | water | water | 18.0 | 390 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 66 (UniProt: Q8IEW2)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Trp 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 31019.8 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2907.2 | |
| All* | Total formula weight | 33927.0 |
