5OJO

Sirtuin 5 from Danio rerio in complex with 3-hydroxy-3-methylglutaryl-CPS1 peptide

Summary for 5OJO

• Entry DOI: 10.2210/pdb5ojo/pdb
• Related: 5OJN
• Descriptor: NAD-dependent protein deacylase sirtuin-5, mitochondrial, Carbamoyl-phosphate synthase [ammonia], mitochondrial, DIMETHYL SULFOXIDE, ... (8 entities in total)
• Functional Keywords: sirtuin, sirt5, deacylase, mitochondria, signaling protein
• Biological source: Danio rerio (Zebrafish); More
• Total number of polymer chains: 3
• Total formula weight: 62492.11

Authors

Pannek, M.,Steegborn, C. (deposition date: 2017-07-22, release date: 2017-11-29, Last modification date: 2024-02-07)

• Primary citation: Pannek, M.,Simic, Z.,Fuszard, M.,Meleshin, M.,Rotili, D.,Mai, A.,Schutkowski, M.,Steegborn, C.; Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features.; Nat Commun, 8:1513-1513, 2017; PubMed: 29138502; DOI: 10.1038/s41467-017-01701-2

Experimental method

X-RAY DIFFRACTION (3.1 Å)