5O1N

Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with N-[(2S)-2-Pyrrolidinylmethyl]-trifluoromethanesulfonamide bound

Summary for 5O1N

• Entry DOI: 10.2210/pdb5o1n/pdb
• Descriptor: Alpha-aminoadipic semialdehyde synthase, mitochondrial, 1,1,1-tris(fluoranyl)-~{N}-[[(2~{S})-pyrrolidin-2-yl]methyl]methanesulfonamide, DIMETHYL SULFOXIDE, ... (6 entities in total)
• Functional Keywords: human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with n-[(2s)-2-pyrrolidinylmethyl]-trifluoromethanesulfonamide bound, oxidoreductase
• Biological source: Homo sapiens (Human)
• Cellular location: Mitochondrion : Q9UDR5
• Total number of polymer chains: 1
• Total formula weight: 55087.36

Authors

Kopec, J.,Rembeza, E.,Pena, I.A.,Strain-Damerell, C.,Goubin, S.,Sethi, R.,Velupillai, S.,Talon, R.,Collins, P.,Krojer, T.,McLaughlin, M.,Burgess-Brown, N.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,von Delft, F.,Arruda, P.,Yue, W.W. (deposition date: 2017-05-18, release date: 2017-05-31, Last modification date: 2024-01-17)

• Primary citation: Kopec, J.,Yue, W.W.; Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with N-[(2S)-2-Pyrrolidinylmethyl]-trifluoromethanesulfonamide bound; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.28 Å)