5NBM

Crystal structure of the Arp4-N-actin(ATP-state) heterodimer bound by a nanobody

Summary for 5NBM
Related5NBL 5NBN
DescriptorActin-related protein 4, Actin, nAct-Nanobody, ... (6 entities in total)
Functional Keywordschromatin remodeling, nanobody, ino80, swr1, nua4, hydrolase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Total number of polymer chains8
Total formula weight232724.89
Authors
Knoll, K.R.,Eustermann, S.,Hopfner, K.P. (deposition date: 2017-03-02, release date: 2018-08-22, Last modification date: 2018-09-19)
Primary citationBuchfellner, A.,Eustermann, S.,Hopfner, K.P.,Knoll, K.R.,Korber, P.,Niebauer, V.,Oberbeckmann, E.,Schall, K.,Schwarz, M.,Stoehr, G.,Tosi, A.
The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling.
Nat. Struct. Mol. Biol., 25:823-832, 2018
PubMed: 30177756
DOI: 110.1038/s41594-018-0115-8
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.4 Å)
Structure validation
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PDB entries from 2021-06-09