5L03
Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate
Summary for 5L03
Entry DOI | 10.2210/pdb5l03/pdb |
Related | 5L12 |
Descriptor | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, N-hydroxy-L-tryptophanamide, ... (4 entities in total) |
Functional Keywords | mep pathway, ispf, inhibitor, complex, lyase |
Biological source | Burkholderia pseudomallei |
Total number of polymer chains | 3 |
Total formula weight | 50981.17 |
Authors | Blain, J.M.,Ghose, D.,Gorman, J.L.,Goshu, G.M.,Ranieri, G.,Zhao, L.,Bode, B.,Meganathan, R.,Walter, R.L.,Hagen, T.J.,Horn, J.R. (deposition date: 2016-07-26, release date: 2017-11-08, Last modification date: 2024-03-06) |
Primary citation | Blain, J.M.,Ghose, D.,Gorman, J.L.,Goshu, G.M.,Ranieri, G.,Zhao, L.,Bode, B.,Meganathan, R.,Walter, R.L.,Hagen, T.J.,Horn, J.R. Synthesis and Characterization of the Burkholderia pseudomallei IspF Inhibitor L-tryptophan hydroxamate To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.469 Å) |
Structure validation
Download full validation report