5KVH

Crystal structure of human apoptosis-inducing factor with W196A mutation

Summary for 5KVH

• Entry DOI: 10.2210/pdb5kvh/pdb
• Descriptor: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: oxidoreductase, flavoprotein, mitochondria, cell death
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 120374.06

Authors

Brosey, C.A.,Nix, J.,Ellenberger, T.,Tainer, J.A. (deposition date: 2016-07-14, release date: 2016-11-16, Last modification date: 2023-10-04)

• Primary citation: Brosey, C.A.,Ho, C.,Long, W.Z.,Singh, S.,Burnett, K.,Hura, G.L.,Nix, J.C.,Bowman, G.R.,Ellenberger, T.,Tainer, J.A.; Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor.; Structure, 24:2067-2079, 2016; PubMed: 27818101; DOI: 10.1016/j.str.2016.09.012

Experimental method

X-RAY DIFFRACTION (2.273 Å)