5KVH
Crystal structure of human apoptosis-inducing factor with W196A mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Apoptosis-inducing factor 1, mitochondrial | polymer | 543 | 59355.4 | 2 | UniProt (O95831) Pfam (PF00070) Pfam (PF14721) | Homo sapiens (Human) | Programmed cell death protein 8 |
| 2 | C, E (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 683 | Chemie (HOH) |
Sequence modifications
A, B: 78 - 613 (UniProt: O95831)
| PDB | External Database | Details |
|---|---|---|
| Met 77 | - | initiating methionine |
| Ala 196 | Trp 196 | engineered mutation |
| Leu 614 | - | expression tag |
| Glu 615 | - | expression tag |
| Val 616 | - | expression tag |
| Leu 617 | - | expression tag |
| Phe 618 | - | expression tag |
| Gln 619 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 118710.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1663.2 | |
| All* | Total formula weight | 120374.1 |
