5HYS
Structure of IgE complexed with omalizumab
Summary for 5HYS
Entry DOI | 10.2210/pdb5hys/pdb |
Descriptor | Epididymis luminal protein 214, Uncharacterized protein, Ig epsilon chain C region, ... (6 entities in total) |
Functional Keywords | immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 301108.26 |
Authors | Pennington, L.F.,Tarchevskaya, S.S.,Sathiyamoorthy, K.,Jardetzky, T.S. (deposition date: 2016-02-01, release date: 2016-06-01, Last modification date: 2023-09-27) |
Primary citation | Pennington, L.F.,Tarchevskaya, S.,Brigger, D.,Sathiyamoorthy, K.,Graham, M.T.,Nadeau, K.C.,Eggel, A.,Jardetzky, T.S. Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. Nat Commun, 7:11610-11610, 2016 Cited by PubMed: 27194387DOI: 10.1038/ncomms11610 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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