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5EU7

Crystal structure of HIV-1 integrase catalytic core in complex with Fab

Summary for 5EU7
Entry DOI10.2210/pdb5eu7/pdb
DescriptorIntegrase, FAB Heavy Chain, FAB light chain, ... (4 entities in total)
Functional Keywordsintegrase, fab, hiv, viral protein
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
More
Cellular locationGag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04585
Total number of polymer chains6
Total formula weight129823.00
Authors
Galilee, M.,Griner, S.L.,Stroud, R.M.,Alian, A. (deposition date: 2015-11-18, release date: 2016-09-28, Last modification date: 2024-01-10)
Primary citationGalilee, M.,Britan-Rosich, E.,Griner, S.L.,Uysal, S.,Baumgartel, V.,Lamb, D.C.,Kossiakoff, A.A.,Kotler, M.,Stroud, R.M.,Marx, A.,Alian, A.
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.
Structure, 24:1936-1946, 2016
Cited by
PubMed: 27692964
DOI: 10.1016/j.str.2016.08.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.64 Å)
Structure validation

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