5EU7
Crystal structure of HIV-1 integrase catalytic core in complex with Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Integrase | polymer | 153 | 16710.1 | 2 | UniProt (P04585) Pfam (PF00665) In PDB | Human immunodeficiency virus 1 (HIV-1) | Pr160Gag-Pol |
2 | E, F | FAB Heavy Chain | polymer | 233 | 24927.6 | 2 | Homo sapiens (Human) | ||
3 | D, C | FAB light chain | polymer | 214 | 23273.8 | 2 | Homo sapiens (Human) | ||
4 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A, B: 57 - 209 (UniProt: P04585)
PDB | External Database | Details |
---|---|---|
Ser 123 | Gly 1270 | conflict |
Thr 124 | Ala 1271 | conflict |
Lys 127 | Arg 1274 | conflict |
Asp 131 | Trp 1278 | engineered mutation |
Lys 185 | Phe 1332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 129823.0 | |
All* | Total formula weight | 129823.0 |