5DNN
Nucleosome core particle containing adducts of gold(I)-triethylphosphane and ruthenium(II)-toluene PTA complexes
Summary for 5DNN
Entry DOI | 10.2210/pdb5dnn/pdb |
Related | 5DNM |
Descriptor | Histone H3.2, dichloro[(1,2,3,4,5,6-eta)-6-methylbenzene]1,3,5-triaza-7lambda~5~-phosphatricyclo[3.3.1.1~3,7~]dec-7-ylruthenium, Histone H4, ... (10 entities in total) |
Functional Keywords | nucleosome, gold antitumour compound, ruthenium antitumour compound, histone binding, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P84233 P62799 P02281 |
Total number of polymer chains | 10 |
Total formula weight | 199920.43 |
Authors | Adhireksan, Z.,Ma, Z.,Davey, C.A. (deposition date: 2015-09-10, release date: 2016-09-14, Last modification date: 2023-11-08) |
Primary citation | Adhireksan, Z.,Palermo, G.,Riedel, T.,Ma, Z.,Muhammad, R.,Rothlisberger, U.,Dyson, P.J.,Davey, C.A. Allosteric cross-talk in chromatin can mediate drug-drug synergy Nat Commun, 8:14860-14860, 2017 Cited by PubMed: 28358030DOI: 10.1038/ncomms14860 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report