5C23
Parkin (S65DUblR0RBR)
Summary for 5C23
Entry DOI | 10.2210/pdb5c23/pdb |
Descriptor | E3 ubiquitin-protein ligase parkin, ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | e3 ligase2, ligase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytosol : O60260 |
Total number of polymer chains | 2 |
Total formula weight | 93044.61 |
Authors | Kumar, A.,Aguirre, J.D.,Condos, T.E.C.,Martinez-Torres, R.J.,Chaugule, V.K.,Toth, R.,Sundaramoorthy, R.,Mercier, P.,Knebel, A.,Spratt, D.E.,Barber, K.R.,Shaw, G.S.,Walden, H. (deposition date: 2015-06-15, release date: 2015-07-29, Last modification date: 2024-01-10) |
Primary citation | Kumar, A.,Aguirre, J.D.,Condos, T.E.,Martinez-Torres, R.J.,Chaugule, V.K.,Toth, R.,Sundaramoorthy, R.,Mercier, P.,Knebel, A.,Spratt, D.E.,Barber, K.R.,Shaw, G.S.,Walden, H. Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. Embo J., 34:2506-2521, 2015 Cited by PubMed: 26254304DOI: 10.15252/embj.201592337 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
Download full validation report