5BYA
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and 1,5-(PCP)2-IP4
Summary for 5BYA
Entry DOI | 10.2210/pdb5bya/pdb |
Related | 5BYB |
Descriptor | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, ADENOSINE-5'-DIPHOSPHATE, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid), ... (7 entities in total) |
Functional Keywords | methylenebisphosphonate, phosphonoacetate, non-hydrolyzable, pyrophosphate mimics, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytosol : O43314 |
Total number of polymer chains | 1 |
Total formula weight | 39480.18 |
Authors | Wang, H.,Shears, S.B. (deposition date: 2015-06-10, release date: 2015-07-22, Last modification date: 2023-09-27) |
Primary citation | Riley, A.M.,Wang, H.,Shears, S.B.,L Potter, B.V. Synthetic tools for studying the chemical biology of InsP8. Chem.Commun.(Camb.), 51:12605-12608, 2015 Cited by PubMed: 26153667DOI: 10.1039/c5cc05017k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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