5BYA
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and 1,5-(PCP)2-IP4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | polymer | 330 | 37568.9 | 1 | UniProt (O43314) Pfam (PF18086) In PDB | Homo sapiens (Human) | Diphosphoinositol pentakisphosphate kinase 2,Histidine acid phosphatase domain-containing protein 1,InsP6 and PP-IP5 kinase 2,VIP1 homolog 2,hsVIP2 |
2 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
3 | A | {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid) | non-polymer | 816.0 | 1 | Chemie (4WZ) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
6 | A | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
7 | water | water | 18.0 | 445 | Chemie (HOH) |
Sequence modifications
A: 41 - 366 (UniProt: O43314)
PDB | External Database | Details |
---|---|---|
Gly 37 | - | expression tag |
Ser 38 | - | expression tag |
Phe 39 | - | expression tag |
Thr 40 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37568.9 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1911.3 | |
All* | Total formula weight | 39480.2 |