5B5K
Crystal structure of Izumo1, the mammalian sperm ligand for egg Juno
Summary for 5B5K
Entry DOI | 10.2210/pdb5b5k/pdb |
Related | 5EJN |
Descriptor | Izumo sperm-egg fusion protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | cell adhesion, fertilization, egg receptor, gamete adhesion, sperm-egg membrane fusion |
Biological source | Mus musculus (Mouse) |
Cellular location | Membrane ; Single-pass type I membrane protein : Q9D9J7 |
Total number of polymer chains | 1 |
Total formula weight | 27791.83 |
Authors | Nishimura, K.,Han, L.,De Sanctis, D.,Jovine, L. (deposition date: 2016-05-11, release date: 2016-07-06, Last modification date: 2023-11-08) |
Primary citation | Nishimura, K.,Han, L.,Bianchi, E.,Wright, G.J.,de Sanctis, D.,Jovine, L. The structure of sperm Izumo1 reveals unexpected similarities with Plasmodium invasion proteins. Curr.Biol., 26:R661-R662, 2016 Cited by PubMed: 27374339DOI: 10.1016/j.cub.2016.06.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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