5B5K

Crystal structure of Izumo1, the mammalian sperm ligand for egg Juno

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005102	molecular_function	signaling receptor binding
A	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
A	0016020	cellular_component	membrane
A	0035036	biological_process	sperm-egg recognition

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	Domain: {"description":"Ig-like C2-type"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Region: {"description":"Important for interaction with IZUMO1R","evidences":[{"source":"PubMed","id":"27309808","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"18952059","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27374339","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5B5K","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

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