5AGA
Crystal structure of the Helicase domain of human DNA polymerase theta in complex with AMPPNP
Summary for 5AGA
Entry DOI | 10.2210/pdb5aga/pdb |
Descriptor | DNA POLYMERASE THETA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, CITRATE ANION, ... (6 entities in total) |
Functional Keywords | transferase, polq, dna repair |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus : O75417 |
Total number of polymer chains | 1 |
Total formula weight | 93959.89 |
Authors | Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Pinkas, D.M.,Kupinska, K.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2015-01-29, release date: 2015-02-25, Last modification date: 2015-12-16) |
Primary citation | Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Gileadi, O. Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure, 23:2319-, 2015 Cited by PubMed: 26636256DOI: 10.1016/J.STR.2015.10.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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