5AER

Neuronal calcium sensor-1 (NCS-1)from Rattus norvegicus complex with D2 dopamine receptor peptide from Homo sapiens

Replaces:  2YOU

Summary for 5AER

• Entry DOI: 10.2210/pdb5aer/pdb
• Related: 5AEQ
• Descriptor: NEURONAL CALCIUM SENSOR 1, D(2) DOPAMINE RECEPTOR, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: signaling protein, neuronal calcium sensor-1, dopamine receptor 2
• Biological source: RATTUS NORVEGICUS (NORWAY RAT); More
• Cellular location: Golgi apparatus, Golgi stack membrane; Peripheral membrane protein: P62168; Cell membrane ; Multi-pass membrane protein : P14416
• Total number of polymer chains: 3
• Total formula weight: 25502.13

Authors

Saleem, M.,Karuppiah, V.,Pandalaneni, S.,Burgoyne, R.,Derrick, J.P.,Lian, L.Y. (deposition date: 2015-01-08, release date: 2015-02-18, Last modification date: 2024-01-10)

• Primary citation: Pandalaneni, S.,Karuppiah, V.,Saleem, M.,Haynes, L.P.,Burgoyne, R.D.,Mayans, O.,Derrick, J.P.,Lian, L.; Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-Protein-Coupled Receptor Kinase 1 (Grk1) Peptides Using Different Modes of Interactions.; J.Biol.Chem., 290:18744-, 2015; PubMed: 25979333; DOI: 10.1074/JBC.M114.627059

Experimental method

X-RAY DIFFRACTION (2.19 Å)