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5AER

Neuronal calcium sensor-1 (NCS-1)from Rattus norvegicus complex with D2 dopamine receptor peptide from Homo sapiens

Replaces:  2YOU
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NEURONAL CALCIUM SENSOR 1polymer19021902.71UniProt (P62168)
Pfam (PF00036)
RATTUS NORVEGICUS (NORWAY RAT)NCS-1, FREQUENIN HOMOLOG, FREQUENIN-LIKE PROTEIN, FREQUENIN-LIKE UBIQUITOUS PROTEIN, NEURONAL CALCIUM SENSOR-1
2B, C
(B, C)
D(2) DOPAMINE RECEPTORpolymer141720.12UniProt (P14416)HOMO SAPIENSDOPAMINE D2 RECEPTOR
3D, E, F
(A)
CALCIUM IONnon-polymer40.13Chemie (CA)
4G
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
5H, I, J
(A, B, C)
waterwater18.030Chemie (HOH)
Sequence modifications
B, C: 430 - 443 (UniProt: P14416)
PDBExternal DatabaseDetails
Ser 443Cys 443engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight25342.8
Non-Polymers*Number of molecules4
Total formula weight159.3
All*Total formula weight25502.1
*Water molecules are not included.

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PDB entries from 2025-12-31

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