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5A3A

Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes (Apo form)

Summary for 5A3A
Entry DOI10.2210/pdb5a3a/pdb
Related5A35 5A3B 5A3C
DescriptorSIR2 FAMILY PROTEIN, GLYCINE, ZINC ION, ... (5 entities in total)
Functional Keywordstransferase, p-ribosyltransferase, metalloprotein, nad-dependent, lipoylation, regulatory enzyme, rossmann fold, zinc binding, ros defense
Biological sourceSTREPTOCOCCUS PYOGENES
Total number of polymer chains1
Total formula weight36031.80
Authors
Primary citationRack, J.G.,Morra, R.,Barkauskaite, E.,Kraehenbuehl, R.,Ariza, A.,Qu, Y.,Ortmayer, M.,Leidecker, O.,Cameron, D.R.,Matic, I.,Peleg, A.Y.,Leys, D.,Traven, A.,Ahel, I.
Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59:309-, 2015
Cited by
PubMed: 26166706
DOI: 10.1016/J.MOLCEL.2015.06.013
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.54 Å)
Structure validation

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