4ZQM

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with XMP and NAD

4ZQM の概要

• エントリーDOI: 10.2210/pdb4zqm/pdb
• 関連するPDBエントリー: 4ZQN 4ZQO 4ZQP 4ZQR
• 分子名称: Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, XANTHOSINE-5'-MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: impdh, delta-cbs, mycobacterium tuberculosis, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42671.26

構造登録者

Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Kavitha, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2015-05-10, 公開日: 2015-06-17, 最終更新日: 2024-05-22)

• 主引用文献: Makowska-Grzyska, M.,Kim, Y.,Gorla, S.K.,Wei, Y.,Mandapati, K.,Zhang, M.,Maltseva, N.,Modi, G.,Boshoff, H.I.,Gu, M.,Aldrich, C.,Cuny, G.D.,Hedstrom, L.,Joachimiak, A.; Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.; Plos One, 10:e0138976-e0138976, 2015; PubMed: 26440283; DOI: 10.1371/journal.pone.0138976

実験手法

X-RAY DIFFRACTION (1.602 Å)