4ZOK

Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

4ZOK の概要

• エントリーDOI: 10.2210/pdb4zok/pdb
• 関連するPDBエントリー: 3QR9 4GIU 4ZOF 4ZOJ
• 分子名称: Anthranilate phosphoribosyltransferase, MAGNESIUM ION, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ... (5 entities in total)
• 機能のキーワード: inhibitor, complex, lobenzarit-like analogue, tb structural genomics consortium, tbsgc, phosphoribosyltransferase, magnesium binding, phosphoribosylpyrophosphate, prpp, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Mycobacterium tuberculosis H37Ra
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79092.76

構造登録者

Evans, G.L.,Baker, E.N.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (登録日: 2015-05-06, 公開日: 2016-05-11, 最終更新日: 2023-09-27)

• 主引用文献: Evans, G.L.,Baker, E.N.,Lott, J.S.; Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).; To be Published,

実験手法

X-RAY DIFFRACTION (2.34 Å)