4ZLP
Crystal Structure of Notch3 Negative Regulatory Region
Summary for 4ZLP
Entry DOI | 10.2210/pdb4zlp/pdb |
Descriptor | Neurogenic locus notch homolog protein 3, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | notch, mutation, disease, autoinhibiton, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 61797.97 |
Authors | Xu, X.,Blacklow, S.C. (deposition date: 2015-05-01, release date: 2015-08-19, Last modification date: 2020-07-29) |
Primary citation | Xu, X.,Choi, S.H.,Hu, T.,Tiyanont, K.,Habets, R.,Groot, A.J.,Vooijs, M.,Aster, J.C.,Chopra, R.,Fryer, C.,Blacklow, S.C. Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region. Structure, 23:1227-1235, 2015 Cited by PubMed: 26051713DOI: 10.1016/j.str.2015.05.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.479 Å) |
Structure validation
Download full validation report