4ZBN

Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor

4ZBN の概要

• エントリーDOI: 10.2210/pdb4zbn/pdb
• 分子名称: DNA (28-MER), Beta-nerve growth factor, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: complex, aptamer, immune system-dna complex, immune system/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Secreted: P01138
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 46860.50

構造登録者

Davies, D.R.,Edwards, T.E. (登録日: 2015-04-15, 公開日: 2015-06-10, 最終更新日: 2015-07-15)

• 主引用文献: Jarvis, T.C.,Davies, D.R.,Hisaminato, A.,Resnicow, D.I.,Gupta, S.,Waugh, S.M.,Nagabukuro, A.,Wadatsu, T.,Hishigaki, H.,Gawande, B.,Zhang, C.,Wolk, S.K.,Mayfield, W.S.,Nakaishi, Y.,Burgin, A.B.,Stewart, L.J.,Edwards, T.E.,Gelinas, A.D.,Schneider, D.J.,Janjic, N.; Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.; Structure, 23:1293-1304, 2015; PubMed: 26027732; DOI: 10.1016/j.str.2015.03.027

実験手法

X-RAY DIFFRACTION (2.447 Å)