4ZBE
Crystal structure of KPC-2 beta-lactamase complexed with avibactam
Summary for 4ZBE
| Entry DOI | 10.2210/pdb4zbe/pdb |
| Related | 4FH4 4ZAM |
| Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, CITRIC ACID, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, ... (4 entities in total) |
| Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Klebsiella pneumoniae |
| Total number of polymer chains | 1 |
| Total formula weight | 28451.89 |
| Authors | Nguyen, N.Q.,van den Akker, F. (deposition date: 2015-04-14, release date: 2016-01-27, Last modification date: 2023-09-27) |
| Primary citation | Krishnan, N.P.,Nguyen, N.Q.,Papp-Wallace, K.M.,Bonomo, R.A.,van den Akker, F. Inhibition of Klebsiella beta-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study. Plos One, 10:e0136813-e0136813, 2015 Cited by PubMed: 26340563DOI: 10.1371/journal.pone.0136813 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report
