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4ZAM

Crystal structure of SHV-1 beta-lactamase bound to avibactam

Summary for 4ZAM
Entry DOI10.2210/pdb4zam/pdb
Related2H5S 4FH4 4ZBE
DescriptorBeta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, ... (4 entities in total)
Functional Keywordshydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceKlebsiella pneumoniae
Total number of polymer chains1
Total formula weight30191.48
Authors
Krishnan, N.,van den Akker, F. (deposition date: 2015-04-13, release date: 2016-01-27)
Primary citationKrishnan, N.P.,Nguyen, N.Q.,Papp-Wallace, K.M.,Bonomo, R.A.,van den Akker, F.
Inhibition of Klebsiella beta-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study.
Plos One, 10:e0136813-e0136813, 2015
Cited by
PubMed: 26340563
DOI: 10.1371/journal.pone.0136813
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.42 Å)
Structure validation

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