4Z9A
Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with phenylmethanesulfonic acid
Summary for 4Z9A
Entry DOI | 10.2210/pdb4z9a/pdb |
Related | 3N8I 4Z99 4Z9B 5PNT |
Descriptor | Low molecular weight phosphotyrosine protein phosphatase, GLYCEROL, SULFATE ION, ... (5 entities in total) |
Functional Keywords | protein tyrosine phosphatase, hydrolase, protein-ligand complex, phenylmethanesulfonic acid |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 19211.69 |
Authors | Trivella, D.B.B.,Fonseca, E.M.B.,Scorsato, V.,Dias, M.P.,Aparicio, R. (deposition date: 2015-04-10, release date: 2015-07-15, Last modification date: 2023-09-27) |
Primary citation | Fonseca, E.M.,Trivella, D.B.,Scorsato, V.,Dias, M.P.,Bazzo, N.L.,Mandapati, K.R.,de Oliveira, F.L.,Ferreira-Halder, C.V.,Pilli, R.A.,Miranda, P.C.,Aparicio, R. Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg.Med.Chem., 23:4462-4471, 2015 Cited by PubMed: 26117648DOI: 10.1016/j.bmc.2015.06.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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