4Z99
Crystal structure of the apo Low Molecular Weight Protein Tyrosine Phosphatase isoform A
Summary for 4Z99
Entry DOI | 10.2210/pdb4z99/pdb |
Related | 3N8I 4Z9A 4Z9B 5PNT |
Descriptor | Low molecular weight phosphotyrosine protein phosphatase (2 entities in total) |
Functional Keywords | lmw-ptpase, lmw-ptp, low molecular weight cytosolic acid phosphatase, red cell acid phosphatase 1, adipocyte acid phosphatase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 18755.27 |
Authors | Fonseca, E.M.B.,Scorsato, V.,Dias, M.P.,de Oliveria, F.L.,Miranda, P.C.M.L.,Aparicio, R. (deposition date: 2015-04-10, release date: 2015-07-15, Last modification date: 2023-09-27) |
Primary citation | Fonseca, E.M.,Trivella, D.B.,Scorsato, V.,Dias, M.P.,Bazzo, N.L.,Mandapati, K.R.,de Oliveira, F.L.,Ferreira-Halder, C.V.,Pilli, R.A.,Miranda, P.C.,Aparicio, R. Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg.Med.Chem., 23:4462-4471, 2015 Cited by PubMed: 26117648DOI: 10.1016/j.bmc.2015.06.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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