4Y1T
Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
Summary for 4Y1T
Entry DOI | 10.2210/pdb4y1t/pdb |
Related | 4Y1S |
Descriptor | Perforin-1, CALCIUM ION (3 entities in total) |
Functional Keywords | perforin, c2 domain, calcium binding, immune system |
Biological source | Mus musculus (Mouse) |
Cellular location | Cytoplasmic granule lumen: P10820 |
Total number of polymer chains | 1 |
Total formula weight | 16675.48 |
Authors | Conroy, P.J.,Yagi, H.,Whisstock, J.C.,Norton, R.S. (deposition date: 2015-02-09, release date: 2015-09-02, Last modification date: 2023-09-27) |
Primary citation | Yagi, H.,Conroy, P.J.,Leung, E.W.,Law, R.H.,Trapani, J.A.,Voskoboinik, I.,Whisstock, J.C.,Norton, R.S. Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290:25213-25226, 2015 Cited by PubMed: 26306037DOI: 10.1074/jbc.M115.668384 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.666 Å) |
Structure validation
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