4XNZ

Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120

Summary for 4XNZ

Entry DOI	10.2210/pdb4xnz/pdb
Related	4JB9 4XMP 4XNY
Descriptor	Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC06B, LIGHT CHAIN OF ANTIBODY VRC06B, ... (5 entities in total)
Functional Keywords	antibody, hiv-1, immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	9
Total formula weight	268180.06
Authors	Zhou, T.,Srivatsan, S.,Kwong, P.D. (deposition date: 2015-01-16, release date: 2015-04-29, Last modification date: 2023-09-27)
Primary citation	Wu, X.,Zhang, Z.,Schramm, C.A.,Joyce, M.G.,Do Kwon, Y.,Zhou, T.,Sheng, Z.,Zhang, B.,O'Dell, S.,McKee, K.,Georgiev, I.S.,Chuang, G.Y.,Longo, N.S.,Lynch, R.M.,Saunders, K.O.,Soto, C.,Srivatsan, S.,Yang, Y.,Bailer, R.T.,Louder, M.K.,Mullikin, J.C.,Connors, M.,Kwong, P.D.,Mascola, J.R.,Shapiro, L. Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161:470-485, 2015 Cited by PubMed: 25865483 DOI: 10.1016/j.cell.2015.03.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.389 Å)

Structure validation