4XNZ

Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019031	cellular_component	viral envelope
C	0002250	biological_process	adaptive immune response
C	0003823	molecular_function	antigen binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005886	cellular_component	plasma membrane
C	0006955	biological_process	immune response
C	0016064	biological_process	immunoglobulin mediated immune response
C	0019814	cellular_component	immunoglobulin complex
C	0050853	biological_process	B cell receptor signaling pathway
C	0070062	cellular_component	extracellular exosome
C	0071735	cellular_component	IgG immunoglobulin complex
C	0071738	cellular_component	IgD immunoglobulin complex
C	0071742	cellular_component	IgE immunoglobulin complex
C	0071745	cellular_component	IgA immunoglobulin complex
C	0071753	cellular_component	IgM immunoglobulin complex
C	0072562	cellular_component	blood microparticle
D	0019031	cellular_component	viral envelope
F	0002250	biological_process	adaptive immune response
F	0003823	molecular_function	antigen binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005886	cellular_component	plasma membrane
F	0006955	biological_process	immune response
F	0016064	biological_process	immunoglobulin mediated immune response
F	0019814	cellular_component	immunoglobulin complex
F	0050853	biological_process	B cell receptor signaling pathway
F	0070062	cellular_component	extracellular exosome
F	0071735	cellular_component	IgG immunoglobulin complex
F	0071738	cellular_component	IgD immunoglobulin complex
F	0071742	cellular_component	IgE immunoglobulin complex
F	0071745	cellular_component	IgA immunoglobulin complex
F	0071753	cellular_component	IgM immunoglobulin complex
F	0072562	cellular_component	blood microparticle
G	0019031	cellular_component	viral envelope
L	0002250	biological_process	adaptive immune response
L	0003823	molecular_function	antigen binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005886	cellular_component	plasma membrane
L	0006955	biological_process	immune response
L	0016064	biological_process	immunoglobulin mediated immune response
L	0019814	cellular_component	immunoglobulin complex
L	0050853	biological_process	B cell receptor signaling pathway
L	0070062	cellular_component	extracellular exosome
L	0071735	cellular_component	IgG immunoglobulin complex
L	0071738	cellular_component	IgD immunoglobulin complex
L	0071742	cellular_component	IgE immunoglobulin complex
L	0071745	cellular_component	IgA immunoglobulin complex
L	0071753	cellular_component	IgM immunoglobulin complex
L	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR201-HIS207

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