4XBF
Structure of LSD1:CoREST in complex with ssRNA
Summary for 4XBF
Entry DOI | 10.2210/pdb4xbf/pdb |
Related | 4KUM |
Descriptor | Lysine-specific histone demethylase 1A, REST corepressor 1, RNA (5'-R(*UP*UP*AP*GP*G)-3'), ... (7 entities in total) |
Functional Keywords | lsd1, lysine specific demethylase, demethylase, demethylation, rna, corest, rest co-repressor 1, amine oxidase, coiled-coil, swirm, chromatin remodelling enzyme, epigenetics, histone modifying enzyme, non-coding rna, ncrna, kdm1a, oxidoreductase-transcription-rna complex, oxidoreductase/transcription/rna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : O60341 Q9UKL0 |
Total number of polymer chains | 3 |
Total formula weight | 92389.17 |
Authors | Luka, Z.,Loukachevitch, L.V.,Martin, W.J.,Wagner, C.,Reiter, N.J. (deposition date: 2014-12-16, release date: 2016-04-27, Last modification date: 2023-09-27) |
Primary citation | Hirschi, A.,Martin, W.J.,Luka, Z.,Loukachevitch, L.V.,Reiter, N.J. G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme. RNA, 22:1250-1260, 2016 Cited by PubMed: 27277658DOI: 10.1261/rna.057265.116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.803 Å) |
Structure validation
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