4XBF

Structure of LSD1:CoREST in complex with ssRNA

4XBF の概要

• エントリーDOI: 10.2210/pdb4xbf/pdb
• 関連するPDBエントリー: 4KUM
• 分子名称: Lysine-specific histone demethylase 1A, REST corepressor 1, RNA (5'-R(*UP*UP*AP*GP*G)-3'), ... (7 entities in total)
• 機能のキーワード: lsd1, lysine specific demethylase, demethylase, demethylation, rna, corest, rest co-repressor 1, amine oxidase, coiled-coil, swirm, chromatin remodelling enzyme, epigenetics, histone modifying enzyme, non-coding rna, ncrna, kdm1a, oxidoreductase-transcription-rna complex, oxidoreductase/transcription/rna
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus : O60341 Q9UKL0
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 92389.17

構造登録者

Luka, Z.,Loukachevitch, L.V.,Martin, W.J.,Wagner, C.,Reiter, N.J. (登録日: 2014-12-16, 公開日: 2016-04-27, 最終更新日: 2023-09-27)

• 主引用文献: Hirschi, A.,Martin, W.J.,Luka, Z.,Loukachevitch, L.V.,Reiter, N.J.; G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme.; RNA, 22:1250-1260, 2016; PubMed: 27277658; DOI: 10.1261/rna.057265.116

実験手法

X-RAY DIFFRACTION (2.803 Å)