4WZI
Crystal structure of crosslink stabilized long-form PDE4B
Summary for 4WZI
Entry DOI | 10.2210/pdb4wzi/pdb |
Related | 4X0F |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ZINC ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | phosphodiesterase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 150127.42 |
Authors | Cedervall, P.,Pandit, J. (deposition date: 2014-11-19, release date: 2015-03-11, Last modification date: 2023-09-27) |
Primary citation | Cedervall, P.,Aulabaugh, A.,Geoghegan, K.F.,McLellan, T.J.,Pandit, J. Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4. Proc.Natl.Acad.Sci.USA, 112:E1414-E1422, 2015 Cited by PubMed: 25775568DOI: 10.1073/pnas.1419906112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
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