4WXP

X-ray crystal structure of NS3 Helicase from HCV with a bound fragment inhibitor at 2.08 A resolution

Summary for 4WXP

• Entry DOI: 10.2210/pdb4wxp/pdb
• Related: 4WXR
• Descriptor: NS3-4 protease, SODIUM ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: helicase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Hepatitis C virus
• Total number of polymer chains: 1
• Total formula weight: 48550.31

Authors

Davies, D.R. (deposition date: 2014-11-14, release date: 2015-12-23, Last modification date: 2023-09-27)

• Primary citation: Buckman, B.O.,Kossen, K.,Misialek, S.,Stevens, S.,Rajagopalan, R.,Ruhmund, D.,Hooi, L.,Snarskaya, N.,Serebryany, V.,Wang, G.,Stoycheva, A.,Nicholas, J.B.,Davies, D.R.,Brunton, S.,Montalbetti, C.,Weddell, D.,Goodwin, C.,Schonfeld, D.,Mather, O.,Cheng, R.,Blatt, L.,Beigelman, L.; crystal structure of NS3 Helicase from HCV with a bound fragment inhibitor; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.08 Å)