4WXG
Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine
Summary for 4WXG
Entry DOI | 10.2210/pdb4wxg/pdb |
Descriptor | Serine hydroxymethyltransferase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, SODIUM ION, ... (5 entities in total) |
Functional Keywords | aldolase, transferase, aldehydes, catalysis, catalytic domain, dimerization, glycine hydroxymethyltransferase, l-allo-threonine, protein binding, threonine aldolase |
Biological source | Streptococcus thermophilus |
Total number of polymer chains | 2 |
Total formula weight | 93925.68 |
Authors | Hernandez, K.,Zelen, I.,Petrillo, G.,Uson, I.,Wandtke, C.,Bujons, J.,Joglar, J.,Parella, T.,Clapes, P. (deposition date: 2014-11-13, release date: 2015-02-04, Last modification date: 2024-01-10) |
Primary citation | Hernandez, K.,Zelen, I.,Petrillo, G.,Uson, I.,Wandtke, C.M.,Bujons, J.,Joglar, J.,Parella, T.,Clapes, P. Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids. Angew.Chem.Int.Ed.Engl., 54:3013-3017, 2015 Cited by PubMed: 25611820DOI: 10.1002/anie.201411484 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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