4WXG

Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine

4WXG の概要

• エントリーDOI: 10.2210/pdb4wxg/pdb
• 分子名称: Serine hydroxymethyltransferase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: aldolase, transferase, aldehydes, catalysis, catalytic domain, dimerization, glycine hydroxymethyltransferase, l-allo-threonine, protein binding, threonine aldolase
• 由来する生物種: Streptococcus thermophilus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93925.68

構造登録者

Hernandez, K.,Zelen, I.,Petrillo, G.,Uson, I.,Wandtke, C.,Bujons, J.,Joglar, J.,Parella, T.,Clapes, P. (登録日: 2014-11-13, 公開日: 2015-02-04, 最終更新日: 2024-01-10)

• 主引用文献: Hernandez, K.,Zelen, I.,Petrillo, G.,Uson, I.,Wandtke, C.M.,Bujons, J.,Joglar, J.,Parella, T.,Clapes, P.; Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids.; Angew.Chem.Int.Ed.Engl., 54:3013-3017, 2015; PubMed: 25611820; DOI: 10.1002/anie.201411484

実験手法

X-RAY DIFFRACTION (2 Å)