4UI2
Crystal structure of the ternary RGMB-BMP2-NEO1 complex
Summary for 4UI2
Entry DOI | 10.2210/pdb4ui2/pdb |
Related | 4UHY 4UHZ 4UI0 4UI1 |
Descriptor | NEOGENIN, BONE MORPHOGENETIC PROTEIN 2, BMP2, REPULSIVE GUIDANCE MOLECULE C, RGMC, HEMOJUVELIN, ... (7 entities in total) |
Functional Keywords | repulsive guidance molecule, bone morphogenetic protein pathway, hemojuvelin, morphogen, axon guidance, cell surface receptor signaling, neogenin, signaling protein |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 84505.59 |
Authors | Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. (deposition date: 2015-03-27, release date: 2015-05-06, Last modification date: 2020-07-29) |
Primary citation | Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein. Nat.Struct.Mol.Biol., 22:458-, 2015 Cited by PubMed: 25938661DOI: 10.1038/NSMB.3016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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