4UEL

UCH-L5 in complex with ubiquitin-propargyl bound to the RPN13 DEUBAD domain

Summary for 4UEL

• Entry DOI: 10.2210/pdb4uel/pdb
• Related: 4UEM
• Descriptor: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5, POLYUBIQUITIN-B, PROTEASOMAL UBIQUITIN RECEPTOR ADRM1, ... (4 entities in total)
• Functional Keywords: hydrolase, deubiquitinating enzyme, dub, uch37, uchl5, proteasome, adrm1, rpn13, deubad, uch, ubiquitin-propargyl
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 3
• Total formula weight: 59359.46

Authors

Sahtoe, D.D.,Van Dijk, W.J.,El Oualid, F.,Ekkebus, R.,Ovaa, H.,Sixma, T.K. (deposition date: 2014-12-18, release date: 2015-03-04, Last modification date: 2019-04-03)

• Primary citation: Sahtoe, D.D.,Van Dijk, W.J.,El Oualid, F.,Ekkebus, R.,Ovaa, H.,Sixma, T.K.; Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.; Mol.Cell, 57:887-, 2015; PubMed: 25702870; DOI: 10.1016/J.MOLCEL.2014.12.039

Experimental method

X-RAY DIFFRACTION (2.3 Å)