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4UB3

DNA polymerase beta closed product complex with a templating cytosine and 8-oxodGMP, 60 s

Summary for 4UB3
Entry DOI10.2210/pdb4ub3/pdb
Related4UAW 4UAY 4UAZ 4UB1 4UB2 4UB4 4UB5 4UBB 4UBC
Descriptor5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... (8 entities in total)
Functional Keywordsdna polymerase, transferase, lyase-dna complex, lyase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight48262.62
Authors
Freudenthal, B.D.,Wilson, S.H.,Beard, W.A. (deposition date: 2014-08-11, release date: 2014-11-12, Last modification date: 2023-09-27)
Primary citationFreudenthal, B.D.,Beard, W.A.,Perera, L.,Shock, D.D.,Kim, T.,Schlick, T.,Wilson, S.H.
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
Nature, 517:635-639, 2015
Cited by
PubMed: 25409153
DOI: 10.1038/nature13886
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.06 Å)
Structure validation

217705

数据于2024-03-27公开中

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