4TX5

Crystal structure of Smac-DIABLO (in space group P65)

Summary for 4TX5

• Entry DOI: 10.2210/pdb4tx5/pdb
• Descriptor: Diablo homolog, mitochondrial, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... (4 entities in total)
• Functional Keywords: smac-diablo, apoptosis
• Biological source: Homo sapiens (Human)
• Cellular location: Mitochondrion : Q9NR28
• Total number of polymer chains: 2
• Total formula weight: 44661.72

Authors

Milani, M.,Mastangelo, E.,Cossu, F. (deposition date: 2014-07-02, release date: 2015-07-15, Last modification date: 2023-12-20)

• Primary citation: Mastrangelo, E.,Vachette, P.,Cossu, F.,Malvezzi, F.,Bolognesi, M.,Milani, M.; The activator of apoptosis Smac-DIABLO acts as a tetramer in solution.; Biophys.J., 108:714-723, 2015; PubMed: 25650938; DOI: 10.1016/j.bpj.2014.11.3471

Experimental method

X-RAY DIFFRACTION (1.8 Å)