4TX5

Crystal structure of Smac-DIABLO (in space group P65)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0006915	biological_process	apoptotic process
A	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
B	0005739	cellular_component	mitochondrion
B	0006915	biological_process	apoptotic process
B	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MPD A 201

Chain	Residue
A	THR46
A	HOH310
A	HOH318
A	HOH323
B	MET103

---

site_id	AC2
Number of Residues	8
Details	binding site for residue MPD A 202

Chain	Residue
A	LEU145
A	ALA149
A	HOH341
A	HOH380
A	TYR53
A	GLY107
A	GLU110
A	MET111

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MPD A 203

Chain	Residue
A	ASP28
A	THR32
B	TYR48
B	GLU150

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MPD A 204

Chain	Residue
A	TYR48
A	ARG85
A	HIS92
A	GLN166
A	GLU167

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ACT A 205

Chain	Residue
A	ARG60
A	SER64
A	THR100
A	HOH351

---

site_id	AC6
Number of Residues	6
Details	binding site for residue ACT A 206

Chain	Residue
A	GLN36
A	TYR39
A	HOH361
B	GLU140
B	ARG147
B	MPD202

---

site_id	AC7
Number of Residues	5
Details	binding site for residue ACT A 207

Chain	Residue
A	GLN118
A	GLU141
A	VAL142
B	THR100
B	THR104

---

site_id	AC8
Number of Residues	5
Details	binding site for residue MPD B 201

Chain	Residue
A	LYS50
A	TYR53
A	LEU145
A	HOH323
B	MET111

---

site_id	AC9
Number of Residues	7
Details	binding site for residue MPD B 202

Chain	Residue
A	TYR39
A	ACT206
A	HOH362
B	TRP102
B	LYS136
B	HIS143
B	HOH322

---

site_id	AD1
Number of Residues	3
Details	binding site for residue ACT B 203

Chain	Residue
B	ASP28
B	THR32
B	ARG162

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