4TX5

Crystal structure of Smac-DIABLO (in space group P65)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Diablo homolog, mitochondrial	polymer	192	21858.3	2	UniProt (Q9NR28) Pfam (PF09057)	Homo sapiens (Human)	Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase, Smac, Smac-DIABLO
2	C, D, E, F, J... (A, B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	6	Chemie (MPD)
3	G, H, I, L (A, B)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4	M, N (A, B)	water	water		18.0	226	Chemie (HOH)

Sequence modifications

A, B: 1 - 184 (UniProt: Q9NR28)

PDB	External Database	Details
Leu 185	-	expression tag
Glu 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43716.5
Non-Polymers*	Number of molecules	10
	Total formula weight	945.2
All*	Total formula weight	44661.7

*Water molecules are not included.