4TRY

Structure of BACE1 complex with a HEA-type inhibitor

Summary for 4TRY

• Entry DOI: 10.2210/pdb4try/pdb
• Related: 4TRW 4TRZ
• Related PRD ID: PRD_002106
• Descriptor: Beta-secretase 1, GLU-ILE-TIH-THC-NVA (3 entities in total)
• Functional Keywords: hydrase proteinase converting, designed inhibitor, hydrase-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 131933.04

Authors

Akaji, K.,Teruya, K.,Akiyama, T.,Sanjho, A.,Yamashita, E.,Nakagawa, A. (deposition date: 2014-06-18, release date: 2015-07-29, Last modification date: 2023-11-08)

• Primary citation: Akaji, K.,Teruya, K.,Akiyama, T.,Sanjho, A.,Yamashita, E.,Nakagawa, A.; Structure of BACE1 complex with an anti-HMC-type inhibitor; to be published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)