4TRY
Structure of BACE1 complex with a HEA-type inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Beta-secretase 1 | polymer | 388 | 43281.8 | 3 | UniProt (P56817) Pfam (PF00026) In PDB | Homo sapiens (Human) | Aspartyl protease 2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2 |
| 2 | D, E, F | GLU-ILE-TIH-THC-NVA | polymer | 4 | 695.8 | 3 | BIRD (PRD_002106) | synthetic construct | syn-HEA type inhibitor |
| 3 | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 131933.0 | |
| All* | Total formula weight | 131933.0 |
